Drug Catalog
Butorphanol:
Opioid Agonist-antagonist - stimulates k; blocks u
0.2 0.8 mg/kg IM, SC, IV (cat, dog)
preanesthetic, sedative, analgesic, antitussive
increased HR, BP, RESP
decreased cardiac output
Panting, ataxia
Stops vomiting, then stimulates digestive tract.
Metabolized by kidneys
REVERSAL : can be used as its own reversal agent
Acepromazine
Phenothiazine blocks a
0.01 0.05 mg/kg IM, SC, IV
tranquilizer, sedative
vasodilation, lowers seizure threshold, antiemetic, antipruritic, stops
epinephrine from causing arrhythmia, hypotension, hypothermia
REVERSAL : none
Glycopyrrolate
Anticholinergic blocks muscarinic receptors of Ach neurotransmitters
0.01 0.02 mg/kg IM, SC
only one to not cross placental barrier
suppresses salivation, less tachycardia, less arrhythmia
decreases acid secretions in stomach good for ulcers
REVERSAL :
Ketamine
Cyclohexamine dissociative anesthetic binds to u & s receptors
5.0 mg/kg IM, SC
superficial analgesic ex. Skin lesions
w/ acepromazine = anticholinergic
enhanced by Butorphanol
increases circ. Sys., CSF pressure (avoid in CNS trauma), salivation,
ocular pressure
decreases RR, tidal volume
bronchodilation, apneustic resp
avoid in cardiac Dx or arrythmias
metabolism : cats kidney
dogs liver
REVERSAL :
Diazepam
Benzodiazepine binds to and activates GABA
0.2 0.4 mg/kg IM
tranquilizer
good for treating seizures
can precipitate when mixed (except when mixed with Ketamine)
light sensitive
increases appetite ( esp. in cats), salivation
decreases heart & resp
dry mouth, lethargy, PUPD, hepatic necrosis (cats), hyperexcitability
metabolized by liver excreted by kidneys
REVERSAL : Flumazinal
Dormitor
A2-adrenergic agonist
Dogs: 10.0 20.0 ug/kg IM; 5.0 10.0 um/kg IV
Cats: 10.0 40.0 um/kg IM ; 10.0 20.0 um/km IV
Sedative, analgesic
Never w/ atropine or glycopyrrolate
Decreases heart rate & resp
Rise in blood pressure, then crashes
Hypothermia, polyuria, emesis, hyperglycemia
REVERSAL : Atipamezol (Antisedan)
Propofol
Acts like Barbiturate can be substituted with Etomidate
4.0 6.0 mg/kg IV SLOWLY
anesthetic (w/in 60 sec, lasts 10 20 min.)
poor analgesic
no Atropine premed. needed
premed tranquilizers decrease amt of Propofol needed
possible vomiting during recovery
Safe for heart patients
min. cardiac effect (possible brady/tachycardia)
min. resp. effect ( brief apnea w/ rapid IV injection)
rapid redistribution & metabolism, some muscle relaxation
safe in patients w/ liver/kidney Dx
Contraindications: respiratory distress
excitation & muscle tremors
can exacerbate systemic infections
high cost, poor storage
REVERSAL: Time
Atropine
Anticholinergic
0.05 mg/kg (0.5 mg/ml)
Mydriatic (counterindicated in patients w/ glaucoma
Increases HR
Decreases salivation, gastric activity
Stops bradycardia, photophobia, crosses blood-brain barrier
Metabolized by kidney
REVERSAL
Morphine
Opioid
Dog: 0.5 mg/kg IM, SC 10-25 mg/ml
Cat: 0.1 mg/kg IM, SC
Analgesia (via CNS)
Effects u receptors
May produce excitement in cats effects are dose dependant
Decreases resp
REVERSAL
Epinepherine
Catecholamine
0.1 mg/kg
increases blood pressure, cardiac output
stimulates the heart muscle
topical vasoconstrictor, bronchodilator bronchodilator
cardiac stimulant,
systemic antiallergic, , and topical antiglaucoma agent; accelerates the heart rate
BAG
Pre-anesthetic
Butorphanol 4 ml
Acepromazine 2 ml
Glycopyrrolate 4 ml
Saline 10 ml
20 ml
Dosage : refer to chart
Reversal:
Ket-Val
Ketamine 50%
Valium (Diazepam) 50%
Dosage : 0.1 0.14 mg/kg IV
Reversal: Flumazinal
Kitty Magic
Ketamine 1 ml
Torbugesic 1 ml
(Butorphanol)
Metedomidine 1 ml
(Dormitor 125 um/kg)
Contraindication: w/ cats less than 4 lbs, need to increase Torbugesic
Dosage: 0.3 ml / 10 lbs IM only
Reversal: Atipamezol (Antisedan)
